S155. SENSORY ATTENUATION DURING AUDITORY PROCESSING IN PARTICIPANTS AT CLINICAL-HIGH RISK FOR PSYCHOSIS: EVIDENCE FROM MAGNETOENCEPHALOGRAPHY
نویسندگان
چکیده
منابع مشابه
Aberrant auditory processing in schizophrenia and in subjects at ultra-high-risk for psychosis.
The N1 and the mismatch negativity (MMN) responses observed in electroencephalographic and magnetoencephalographic (MEG) recordings reflect sensory processing, sensory memory, and adaptation and are usually abnormal in patients with schizophrenia. However, their differential sensitivity to ultra-high-risk (UHR) status is controversial. The current study evaluated the sensitivity of MEG N1m, N1m...
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BACKGROUND Some high-risk (HR) mental states for psychosis may lack diagnostic specificity and predictive value. Furthermore, psychotic-like experiences found in young populations may act not only as markers for psychosis but also for other non-psychotic psychiatric disorders. A neglected consideration in these populations is the effect of substance misuse and its role in the development of suc...
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AIM High rates of anxiety have been observed in youth at clinical high risk (CHR) of developing psychosis. In CHR, anxiety often co-occurs with depression, and there is inconsistent evidence on anxiety in relation to transition to psychosis. The aim of this study was to examine: (i) the prevalence of anxiety disorders in individuals at CHR; (ii) clinical differences between those with and witho...
متن کاملAuditory cortex responsiveness during talking and listening: early illness schizophrenia and patients at clinical high-risk for psychosis.
OBJECTIVE The corollary discharge mechanism is theorized to dampen sensations resulting from our own actions and distinguish them from environmental events. Deficits in this mechanism in schizophrenia may contribute to misperceptions of self-generated sensations as originating from external stimuli. We previously found attenuated speech-related suppression of auditory cortex in chronic patients...
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The psychosis high-risk state is accompanied by alterations in functional brain activity during working memory processing. We used binary automatic pattern-classification to discriminate between the at-risk mental state (ARMS), first episode psychosis (FEP) and healthy controls (HCs) based on n-back WM-induced brain activity. Linear support vector machines and leave-one-out-cross-validation wer...
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ژورنال
عنوان ژورنال: Schizophrenia Bulletin
سال: 2018
ISSN: 0586-7614,1745-1701
DOI: 10.1093/schbul/sby018.942